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.Objectives:Apolipoprotein (apo) E phenotype has been associated with inflammation markers. The determinants of these associations and the relationship between novel inflammation marker, resistin, and apoE phenotype are studied here.Methods and Results:Middle-aged subjects of the population- based cohort (n = 526) of the OPERA– study were studied. Intima-media thickness (IMT) was measured with carotid...
.Objectives and design:In this study, we examine the relationship between C5a and activation of cysteine aspartic acid protease 8 (caspase 8) in human umbilical vein endothelial cells (HUVEC).Materials or subjects:Primary cultures of HUVEC were used.Treatments:Recombinant human C5a (50 ng/ml) was used in the presence or absence of 10 μg/ml cycloheximide (CHX). Methods:HUVEC were treated with C5a...
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